SUPERFICIAL PERIVASCULAR DERMATITIS

BALLOONING


Ballooning mostly

Lymphocytes predominate Steel-gray nuclei and margination of chromatin Herpesvirus infection
Individual necrotic keratinocytes and multinucleated epithelial giant cells Measles

Interface

Lymphocytes predominate Individual necrotic keratinocytes, normal cornified layer Erythema multiforme
Individual necrotic keratinocytes,prominent granular layer, parakeratosis Graft vs. host reaction
Eosinophils and neutrophils prominent Individual necrotic keratinocytes, ballooning, normal cornified layer Fixed drug eruption, superficial
Individual necrotic keratinocytes, spongiosis, neutrophils as solitary units within epidermis Toxic shock syndrome

Psoriasiform

Lymphocytes predominate Intracytoplasmic inclusion bodies Orf
Milker's nodule