MOSTLY LOBULAR
| Vasculitis | Small vessel | Venules, globi numerous | Erythema nodosum
leprosum Lucio's phenomenon |
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| Large vessel | Artery | Nodular vasculitis Crohn's disease |
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| No vasculitis | Few or no inflammatory cells | Needle-shaped clefts in adipocytes | Sclerema neonatorum | |
| Lymphocytes predominant | superficial and deep perivascular dermal infiltrate | Cold panniculitis | ||
| Lymphocytes abnormal | Lymphoma, e.g.; mycosis fungoides, angiocentric | |||
| Lymphocytes, plasma cells, nuclear "dust" of lymphocytes often | Lupus erythematosus profundus | |||
| Neutorophils | Extensive fat necrosis with sign of saponification | Pancreatic panniculitis | ||
| No other findings | Factitial panniculitis Bacterial infections |
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| Neutorophils and histicytes | Causative organisms identifiable by specialized stains | Mycobacterial infections | ||
| Causative organisms identifiable by hematoxyline and eosin usually | Deep fungal infections Parasitic infections |
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| Histiocytes (granulomatous) | No needle-shaped cleft in adipocytes | Focal | Sarcoidosis | |
| Patchy | Traumatic fat necrosis | |||
| Diffuse | Lipodystrophy | |||
| Needle-shaped clefts mostly in histiocytes, sometimes in adipocytes | Subcutaneous fat
necrosis/ Poststeroid panniculitis |
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