PANNICULITIS

MOSTLY LOBULAR

Vasculitis Small vessel Venules, globi numerous Erythema nodosum leprosum
Lucio's phenomenon
Large vessel Artery Nodular vasculitis
Crohn's disease
No vasculitis Few or no inflammatory cells Needle-shaped clefts in adipocytes Sclerema neonatorum
Lymphocytes predominant superficial and deep perivascular dermal infiltrate Cold panniculitis
Lymphocytes abnormal Lymphoma, e.g.; mycosis fungoides, angiocentric
Lymphocytes, plasma cells, nuclear "dust" of lymphocytes often Lupus erythematosus profundus
Neutorophils Extensive fat necrosis with sign of saponification Pancreatic panniculitis
No other findings Factitial panniculitis
Bacterial infections
Neutorophils and histicytes Causative organisms identifiable by specialized stains Mycobacterial infections
Causative organisms identifiable by hematoxyline and eosin usually Deep fungal infections
Parasitic infections
Histiocytes (granulomatous) No needle-shaped cleft in adipocytes Focal Sarcoidosis
Patchy Traumatic fat necrosis
Diffuse Lipodystrophy
Needle-shaped clefts mostly in histiocytes, sometimes in adipocytes Subcutaneous fat necrosis/
Poststeroid panniculitis