INTRAEPIDERMAL VESICULAR AND PUSTULAR DERMAITIS
ACANTHOLYSIS
| Upper spinous/ granular | Bacteria in blister | Bullous impetigo | |
| No bacteria in blister | Pemphigus foliaceus Drug-induced pemphigus foliaceus SSSS |
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| Midspinous | Steel-gray nuclei | Herpes virus infections | |
| No steel-gray nuclei | Blister beetle dermatitis | ||
| Suprabasal | Focal | Eosinophils, no spongiosis, no crusts | Darier's disease |
| Eosinophils, spongiosis, oftern crusts | Grover's disease | ||
| Diffuse | Epidermis mostly cohesive | Pemphigus vulgaris Drug-induced pemphigus foliaceus |
|
| Epidermis mostly acantholytic, at lease in foci | Hailey-Haileydisease | ||