Pseudolymphoma
Simulators of B-cell lymphoma
Fully developed
Nodular and/or diffuse infiltrate made up mostly of small lymphocytes within the dermis and, sometimes, in the upper part of the subcutaneous fat | |
Infiltrate usually denser in the upper part ("top heavy") or equally dense throughout | |
Epithelial and nonepithelial structures of adnexa tending to be spared | |
Vascularture within the dense infiltrate prominent, the number of thick-walled blood vessels lined by plump endothelial cells appearing to be increased in number | |
Infiltrate often mixed and containing plasma cells, histiocytes, and eosinophils, in addition to preponderant small lymphocytes | |
Lymphoid follicles present sometime (less than 5%) | |
"Tingible bodies"(polychrome bodies, lymphocytic nuclear "dust"), especially noticeable in germinal centers but also in their absence | |
Some lymphocytes with large nuclei and some in mitosis; strikingly abnormal lymphocytes not predominating in even a single high-power field |