Pseudolymphoma

Simulators of B-cell lymphoma

Fully developed

Nodular and/or diffuse infiltrate made up mostly of small lymphocytes within the dermis and, sometimes, in the upper part of the subcutaneous fat
Infiltrate usually denser in the upper part ("top heavy") or equally dense throughout
Epithelial and nonepithelial structures of adnexa tending to be spared
Vascularture within the dense infiltrate prominent, the number of thick-walled blood vessels lined by plump endothelial cells appearing to be increased in number
Infiltrate often mixed and containing plasma cells, histiocytes, and eosinophils, in addition to preponderant small lymphocytes
Lymphoid follicles present sometime (less than 5%)
"Tingible bodies"(polychrome bodies, lymphocytic nuclear "dust"), especially noticeable in germinal centers but also in their absence
Some lymphocytes with large nuclei and some in mitosis; strikingly abnormal lymphocytes not predominating in even a single high-power field