Herpes virus infection

Fully developed

Moderately dense superficial and, sometimes, superficial and deep perivascular and interstitial infiltrate of lymphocytes and neutrophils
Edema of the papillary dermis
Fibrin sometimes present in walls of venules in the upper part of the dermis, and, in that circumstance, neutrophils are sometimes accompanied by nuclear "dust"
Some multinucleate ballooned keratinocytes in the epidermis and, sometimes, in infundibula, sebaceous units, and eccrine ducts; nuclei steel-gray with accentuation of uncleoplasm at their periphery
Vesicles consequent to ballooning associated with reticular alteration
Acantholytic cells, some necrotic, within the intraepidermal blister
Some intraepidermal vesicles rupturing and thereby becoming subepidermal

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