Herpes virus infection
Fully developed
Moderately dense superficial and, sometimes, superficial and deep perivascular and interstitial infiltrate of lymphocytes and neutrophils | |
Edema of the papillary dermis | |
Fibrin sometimes present in walls of venules in the upper part of the dermis, and, in that circumstance, neutrophils are sometimes accompanied by nuclear "dust" | |
Some multinucleate ballooned keratinocytes in the epidermis and, sometimes, in infundibula, sebaceous units, and eccrine ducts; nuclei steel-gray with accentuation of uncleoplasm at their periphery | |
Vesicles consequent to ballooning associated with reticular alteration | |
Acantholytic cells, some necrotic, within the intraepidermal blister | |
Some intraepidermal vesicles rupturing and thereby becoming subepidermal |